EggNOG 데이터베이스

2023-08-04

Genomics

EggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups) 

목적: EggNOG 데이터베이스는 orthology 정보와 유전자 진화 히스토리 정보, 유전자 기능주석 정보 등을 통합한 공개 데이터베이스 입니다. 2018년도에 버전 5.0 으로 확장되어 출시되었습니다. 자세한 사항은 아래의 글을 참조바랍니다.

eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups) is a public resource in which thousands of genomes are analyzed at once to establish orthology relationships between all their genes. Compared to similar databases, eggNOG focuses on providing: (i) comprehensive functional annotations for the inferred orthologs, (ii) predictions across thousands of genomes covering the three domains of life and viruses, and iii) hierarchical resolution of orthology assignments and fine-grained relationships (i.e. in-paralogies) based on phylogenetic analysis.

저장된 정보: orthology relationships, gene evolutionary histories, functional annotation 정보를 포함함 

통계: 5,090개의 Organisms, 2,502개의 Viruses, 4.4백만개의 Orthologous Groups 등의 정보를 포함함

홈페이지: http://eggnog5.embl.de/ 

레퍼런스: “eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses”. Jaime Huerta-Cepas, Damian Szklarczyk, Davide Heller, Ana Hernández-Plaza, Sofia K Forslund, Helen Cook, Daniel R Mende, Ivica Letunic, Thomas Rattei, Lars J Jensen, Christian von Mering, Peer Bork, Nucleic Acids Res. 2019 Jan 8; 47(Database issue): D309–D314. doi: 10.1093/nar/gky1085

KBDS에 저장된 위치: KBDS인프라의 /scratch/database/EggNOG/ 에 접근하여 사용 가능함